In four reports, autologous or allogenic BG was employed: autologous osteochondral calcaneus BG in one analyze [36], autologous graft harvested from your ipsilateral talar articular aspect in A further research [37], autologous cancellous bone in the distal tibial metaphysis in a 3rd examine [38], in addition to a commercially readily available and meals and Drug Administration-accepted particulated juvenile cartilage allograft transplantation (PJCAT) inside a fourth review [39].
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The risk of bias, evaluated While using the Downs and Black checklist showed an All round poor excellent of your incorporated reports, with a median rating of eighteen.
Among these methods, MF is one of the most applied strategies as a result of its ease of use and talent to deliver bone marrow mesenchymal stem cells (BMSCs) towards the lesion web-site. different studies have demonstrated that This method tends to lead to the development of fibrous-kind cartilage after some time [15,16].
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